Completely no, quality's the same. I also bought waterproof (beerproof), dustproof, shockproof case for Ipad so it's safe on the table in club or at the festival. This option is waaaaaay better than using delicate, much more expensive computer.
Only disadvatage is that Traktor dj app got only two channels (if you will connect it to the S4 it will only use two channels) and there is no option to use remix decks. But size of the tablet, everything-proof case and smootlhy working plug and play wins for me.
When I started playing like this even laptop dj's looked at me a bit strange, but I always told them this is better